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Preparation, characterization and in vivo studies of amorphous solid dispersion of gambogic acid with meglumine

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The aim of this study was to develop an amorphous solid dispersion system utilizing meglumine (MG) as an alkalizing matrix to improve the dissolution rate and oral bioavailability of gambogic acid (GA). Solid dispersion of GA with MG (GA/MG-SD) was fabricated ... ...