Development of a Stable Microemulsion - Based Delivery of Amlodipine Besylate: A Promising Approach for Topical Treatment of Anal Fissures
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Anal fissures (AF) are painful anorectal disorders for which topical calcium - channel blockers (CCBs), such as amlodipine besylate (AMD), are recommended to avoid systemic adverse effects associated with oral therapy. However, the topical use of AMD has been ... ...