Dual-Functional Amine-Modified Aluminum-Doped MCM-41 Nanoparticles for Concurrent Zoledronic Acid Adsorption and Geranylgeraniol Delivery for Prevention of Medication-Related Osteonecrosis of the Jaw
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This study aimed to develop a bifunctional nanomaterial that could simultaneously adsorb zoledronic acid (ZA) and release geranylgeraniol (GGOH) to reverse ZA-induced cytotoxicity. The synthesized aluminum-doped mesoporous silica nanomaterial (AM) was subseque... ...