Photo-Controlled MUC1 Ablation via Steric Locking of Turn-On Reactors Enhances Pyroptosis-Immunotherapy of Triple Negative Breast Cancer
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Mucin 1 (MUC1) is aberrantly upregulated in triple-negative breast cancer (TNBC) cells and presents major roles in orchestrating TNBC pathogenesis and therapeutic resistance. Herein, a bioorthogonal MUC1-binding strategy is reported to install MUC1-lockable ag... ...