Biosynthesis of Trichobisabolins Involves a UbiA-Type Terpene Cyclase for trans-Zingiberenol Generation and a Single Cytochrome P450 Catalyzing the γ-Butenolide Formation from an Isoprene Unit
{{output}}
Through genome mining, a conserved biosynthetic gene cluster from the biocontrol Trichoderma species was identified and characterized to be responsible for the biosynthesis of γ-butenolide-containing sesquiterpenoid trichobisabolin B. The biosynthetic pathway... ...