Exposure of dams to Elexacaftor/ Tezacaftor/Ivacaftor during pregnancy and breastfeeding induces reversible alterations in newborn wild type CD-1 mice
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Background: We previously demonstrated that Tezacaftor inhibits the enzyme (DEGS) that converts dihydroceramides (dHCer) into ceramides, thus producing accumulation of dHCer in various cells and tissues. We here conducted an in-v... ...
