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Mitochondrial cargo quality determines the paracrine effects of extracellular vesicles derived from vascular endothelial cells

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Cell-derived extracellular vesicles (EV) are mediators of intercellular communication with increased circulating levels of endothelial cell-derived EV (EC-EV) reported in cardiovascular diseases (CVD). The EC-EV ability to elicit either detrimental or restorat... ...