CD21 primes extrafollicular differentiation of autoreactive B cells in a TLR7-driven lupus model
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The extrafollicular (EF) B cell differentiation pathway has emerged as a prominent source of autoantibody-secreting cells (ASCs) in systemic lupus erythematosus (SLE). CD21loCD11c+ B cells are associated with aging, infection, and autoimmunity. They are key co... ...
