Notum disrupts Wnt/β-catenin-mediated BMP9 osteogenesis in MSCs: implications for bone regeneration
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Purpose/aim: Bone morphogenetic protein 9 (BMP9) is a cytokine with potent osteoinductive activity, although its precise regulatory mechanisms remain incompletely elucidated. NOTUM, a secreted palmitoleoyl-protein carboxylesteras... ...
