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Non-invasive Temporal Interference Stimulation of the Hippocampus Suppresses Epileptic Biomarkers in Patients with Epilepsy: Biophysical Differences between Kilohertz and Amplitude Modulated Stimulation

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Introduction: Medication-refractory focal epilepsy creates a significant clinical challenge, with approximately 30% of patients deemed ineligible for surgery due to involvement of eloquent cortical regions within the epileptogeni... ...