Thiazole pharmacophore-based discovery of novel SGLT2 inhibitors using virtual screening, molecular docking, and molecular dynamics simulation for diabetic nephropathy
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Diabetic nephropathy (DN), a serious complication of chronic diabetes mellitus, remains a leading cause of end-stage renal disease (ESRD). Although therapies targeting the renin-angiotensin-aldosterone system (RAAS) exist, many patients still face progressive ... ...
