Genetic ablation of p16 leads to pulmonary remodeling, pro-senescence response, and immune modulation in mice exposed to low-dose, Sub-chronic, environmental tobacco smoke
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Objective: Cyclin-dependent kinase inhibitor 2 A, CDKN2A/p16INK4a (p16), is a gene involved in regulating the cell cycle, cellular senescence, and inflammatory responses. The role of p16 in pulmonary immune-inflammatory and cellu... ...