Design, synthesis, and evaluation of 1, 3-dioxo- N- phenylisoindoline-5-carboxamide derivatives as potent reversible inhibitors of human monoamine oxidase B with neuroprotective properties
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A series of 1, 3-dioxo-N-phenylisoindoline-5-carboxamide derivatives were designed, synthesised and evaluated as potent human monoamine oxidase B (hMAO-B) inhibitors with neuroprotective properties. The structure-activity relationship (SAR) was summarised. The... ...
