Tame the Hydra's head: Targeting bone marrow maladaptive myelopoiesis to reverse macrophage-mediated immunosuppression in cancer
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Immunosuppressive monocyte-derived macrophages are key targets in cancer therapy; however, the mechanisms of their replenishment and functional plasticity remain elusive. In a recent issue of Nature, Hedge et al. challenge the conventional view that immunosupp... ...
