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Therapeutic potential of AAV8-mediated IL-17RA extracellular domain gene delivery in an imiquimod-induced mouse model of psoriasis

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Objective: To investigate the therapeutic effects of adeno-associated virus serotype 8 (AAV8)-mediated delivery of the extracellular domain of IL-17RA (IL-17RA(ECD)) on imiquimod (IMQ)-induced psoriasiform dermatitis in mice. ... ...