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Real-World Efficacy and Safety of Zishenyizhi Pill in Cognitive Impairment Associated with Cerebral Small Vessel Disease: A Multicenter Prospective Observational Study

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Background: Cerebral small vessel disease (CSVD) is a leading cause of vascular cognitive impairment, contributing to 36%-67% of vascular dementia cases. Current therapies, primarily cholinesterase inhibitors, offer limited effic... ...