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Cartilage extracellular matrix regeneration with 10-gingerol via KEAP1-NRF2-ARE axis for osteoarthritis therapy

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Osteoarthritis (OA) is characterized by oxidative stress, inflammation, and apoptosis, leading to an imbalance between cartilage extracellular matrix (ECM) synthesis and degradation. Gingerols can regulate multiple biological activities, indicating their thera... ...