Use of methotrexate carried in lipid core nanoparticles in rats with endotoxemia: a possible new strategy for the treatment of the cardiac dysfunction in sepsis
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Cardiac dysfunction is a major cause of death in endotoxemia. Previously, we showed that methotrexate (MTX) carried in lipid-core nanoparticles (LDE) can modulate immune response and increase myocardial angiogenesis. The aim was to test the effects of LDE-meth... ...
