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Prime editing corrects the dilated cardiomyopathy causing RBM20-P633L-mutation in human cardiomyocytes

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Prime editing (PE) is an innovative next-generation gene editing tool that has therapeutic potential in post-mitotic organs, such as the human heart. However, its applicability and efficiency in non-proliferating cells, e.g., human cardiomyocytes, is not yet e... ...