Autism risk variants in DLG4 ortholog increase penetrance of uncommon individual behavioral trait in Caenorhabditis elegans
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Autism is a largely neurogenetic condition characterized by atypical behaviors, including increased prevalence of motor stereotypies. We used Caenorhabditis elegans to model the T611I variant in the DLG4 ortholog dlg-1 . During phenotyping, we found that some ... ...
