The protein-protein interaction between two spliced leader trans -splicing factors is mediated by two interlinked α-helical domains
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SNA-1 and SNA-2 proteins are involved in spliced leader trans -splicing in Caenorhabditis elegans . They are components of the SL1 snRNP that donates the spliced leader 1 RNA which replaces the 5' end of most pre-mRNAs. SNA-1 and SNA-2 bind to each other, but... ...