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Lipoic acid zwitterionic polymer engineered nanozymes ferried by neutrophil reprogramming ischemic microenvironment for stroke treatment

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The accumulation of pathological reactive oxygen species (ROS) after reperfusion of ischemic stroke (IS) triggers the cascade of "oxidative stress-mitochondrial apoptosis-NLRP3 pyroptosis", which aggravates neuronal death and neuroinflammation. In view of th... ...