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Oxygen-Vacancy-Engineered Self-Regenerative Nanozymes in Dual-Signal-Responsive Dynamic Hydrogels: A Closed-Loop Therapeutic Strategy for Diabetic Wound Microenvironment Remodeling

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Diabetic wounds are trapped in a self-perpetuating pathological triad of hypoxia, infection, and oxidative stressdisrupting physiological wound healing and causing recalcitrant nonhealing ulcerswhile conventional therapies, limited by static interventions and ... ...