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Deep learning approach for DCE-MRI parameter estimation: Evaluating signal intensity and concentration-time curve-based convolution-neural-networks

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Dynamic contrast-enhanced MRI (DCE-MRI) is common technique for assessing tissue perfusion and permeability in brain tumors (e.g., gliomas), using generalized tracer kinetic (GTK) analysis. However, conventional non-linear least squares (NLLS) methods are comp... ...