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Cationic nanoparticle targets cGAS-STING axis to drive functional orofacial muscle regeneration

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Post-injury orofacial muscle is highly prone to fibrosis, partly due to a dysregulated microenvironment shaped by cell-free DNA (cfDNA). Muscle stem cell, i.e., muscle satellite cell (MuSCs), are key mediators of regeneration and are highly sensitive to such c... ...