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LncRNA Gm17586 Reduces HSCs Activation by Increasing SIRT1 Transcript Activity to Enhance Smad3 Deacetylation

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Long noncoding RNAs (lncRNAs) play crucial roles in liver fibrosis (LF). We previously showed that the key lncRNA Gm17586 is involved in LF, but its molecular mechanism remains unclear. Primary hepatic stellate cells (HSCs) were isolated from LF mice. Real-tim... ...