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Degradable biomimetic stent with hydrogel and directional TGF-loaded nano-fiber membrane for the treatment of esophageal fistula

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Esophageal fistulas (EFs) arising from esophageal cancer, trauma, or iatrogenic injury can lead to severe complications. While covered metal stents can effectively occlude EFs, their long-term implantation may result in migration, in-stent stenosis, and bleedi... ...