Reversing fibroblast-to-myofibroblast transition using surface-engineered nanoparticles to potentially ameliorate fibrotic diseases
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Fibroblast-to-myofibroblast transition (FMT) is cellular transformation process driving the pathogenesis of fibrotic disorders such as pulmonary fibrosis and scleroderma. Despite advances in anti-fibrotic therapies, existing treatments primarily slow disease p... ...