Multi-modal single-cell platform for nanoparticle-enhanced time-series metabolic profiles of CD8+ T cell exhaustion in tumor immunosurveillance
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Cytotoxic T cells (CD8+) play a pivotal role in immunosurveillance by identifying and eliminating tumor cells. However, the onset of CD8+ T cell exhaustion, characterized by overexpression of immune checkpoint receptors, impairs their function, allowing tumor ... ...
