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The DOPA Scaffold: Tracing Catechol Chemistry from Prebiotic Earth to Cognitive Agency

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L-3,4-dihydroxyphenylalanine (DOPA) is primarily defined by its role as the precursor to catecholamine neurotransmitters, a view substantiated by its status as the gold-standard treatment for Parkinson's disease. This framing obscures its profound evolutionar... ...