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Bridging In Vitro and In Vivo Inhalation Toxicity: Volatile Organic Compounds Elicit Similar Transcriptomic Points of Departure in Human Airway Cells and Mouse Respiratory Tract

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In vitro differential gene expression analysis has been proposed as a higher throughput alternative to traditional animal toxicity testing for chemical risk assessment, but few studies have compared transcriptomic differences between respiratory in vitro syste... ...