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Microenvironment-responsive hydrogels for spatiotemporal delivery of epigallocatechin gallate and BMP-2 to promote osteoporotic bone defect repair

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Regenerating osteoporotic bone defects is still a major challenge. Conventional bone tissue engineering materials often fail to achieve on-demand drug delivery. At the same time, the therapeutic logic of osteoporotic bone defects requires spatiotemporal drug d... ...