A Targeted LC-MS/MS-based Quantitative Assay for Detecting Plasma Factor XIII A/B Subunit Deficiency
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Factor XIII (FXIII) is a heterotetramer that plays a critical role in the coagulation cascade, facilitating fibrin crosslinking to stabilize clots. Congenital or acquired deficiency of FXIII A or B subunits can lead to prolonged bleeding. Existing ELISA-based ... ...