Mitogen-Activated Protein Kinase Driven Rare Gynecologic Cancers and Evolving Therapeutic Targets
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The mitogen-activated protein kinase (MAPK) cascade is a critical pathway involved in cancer cell survival as well as resistance to drug therapy. Phosphorylation of extracellular signal-regulated kinase 1 (ERK1) and extracellular signal-regulated kinase 2 (ERK... ...