Rocker-Switch Mechanism of Choline Transmembrane Transport in FLVCR2: Dynamic Latch Residues and Cooperative Regulation of Transmembrane Helices
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As a key member of the major facilitator superfamily, FLVCR2 plays a crucial role in choline transport. However, the kinetic mechanism and substrate recognition mode of its transmembrane transport remain elusive. Here, we integrate long-time-scale molecular dy... ...
