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Organ Preserving or Radical Surgery? A Systematic Review and Meta-Analysis of Transanal Local Excision Versus Total Mesorectal Excision After Neoadjuvant Therapy for Rectal Cancer

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Background: Total mesorectal excision (TME) is the standard surgical treatment for rectal cancer. Transanal local excision (TLE) after neoadjuvant chemoradiotherapy (nCRT) is an organ-preserving option, avoiding morbidity of TME.... ...