Dose Optimization and Receptor Utilization of Prostaglandin E Analogs for Radioprotection and Radiomitigation of H-ARS and DEARE
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The prostaglandin E2 (PGE2) analog 16, 16 dimethyl-PGE2 (dmPGE2) administered prior to lethal irradiation protects against mortality from the hematopoietic acute radiation syndrome (H-ARS) and the chronic delayed effects of acute radiation exposure (DEARE). Dm... ...