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Des-Aspartate Angiotensin-1: A Dual-Targeted Therapeutic for Perivascular Inflammation and Vascular Dysfunction in Obesity

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Perivascular adipose tissue (PVAT) influences the tone of vascular function through its endocrine, paracrine, and vasocrine functions. Obesity-induced PVAT inflammation promotes vascular dysfunction by shifting its secretory profile to a proinflammatory state.... ...