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SerpinB9 sustains CIITA to orchestrate MHC-II expression and Th1 differentiation in β-glucan-induced macrophages

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Whole glucan particles (WGP) enhance macrophage immune function, while serine protease inhibitor B9 (SerpinB9)-a molecule known to promote tumor immune escape-has an unclear role in WGP-induced macrophage function. In this study, we found that SerpinB9 knockou... ...