Microvascular Homeostasis Is Compromised in Pancreatic Islets in a Mouse Model of β-Cell Loss and Low-Grade Inflammation
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Pericyte dysfunction is an early event in type 1 diabetes in humans, but how it affects islet microvascular homeostasis in vivo is unknown. We sought to determine whether vascular integrity and blood flow regulation in islets were impaired in a model of partia... ...