Broad H3K4me3 domains support oocyte genome silencing and maturation but are dispensable for repression in early embryos
{{output}}
Epigenetic reprogramming and embryonic genome activation (EGA) are crucial events during early development. Establishment of distinctive broad histone H3 lysine 4 trimethylation (H3K4me3) domains in the oocyte is necessary for genome silencing, and their remov... ...
