Microbial catalyzed derivatization of canrenone with Glomerella fusarioides, and Cunninghamella blakesleana, and evaluation of aromatase inhibitory activity of the resulting metabolites
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The purpose of this study was to identify potential aromatase inhibitors, which might play a role in preventing breast cancer. For this fungal-catalyzed microbial transformation of anti-mineralocorticoid, canrenone (1), was catalyzed by Glomerella fusarioides,... ...
