Proinflammatory and cytotoxic CD38+HLA-DR+ effector memory CD8+ T cells are peripherally expanded in human cardiac allograft vasculopathy
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Interferon-γ (IFNG) is thought to play a central role in the pathogenesis of cardiac allograft vasculopathy (CAV) in heart transplant (HTx) patients. However, peripheral lymphocytes participating in the IFNG-axis remain largely unknown in human CAV. Using per... ...