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Covalent Organic Framework-Based Artificial Antioxidases with π-Electron Delocalization and Asymmetric Coordination Sites for Superior Inflammation Inhibition and Oral Bone Modulation

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Periodontitis-induced alveolar bone loss represents a complex therapeutic challenge that demands simultaneous resolution of chronic inflammation and restoration of bone homeostasis. Drawing inspiration from natural antioxidases, the de novo design of an interl... ...