Genetic Variations of the FUT3 Gene in Le(a-b-) Individuals and Their Association with Lewis Antibody Responses
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Background: The biosynthesis of Lewis (Le) antigens depends on the FUT3 gene, encoding an α(1,3/4)-fucosyltransferase. Individuals lacking functional FUT3 exhibit a Le(a-b-) phenotype, regardless of secretor status. Methods: This study determined the prevalen... ...
