ERAP1 Allotypes 2 and 10 Differentially Regulate the Immunopeptidome of Melanocytes
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Endoplasmic reticulum aminopeptidase 1 (ERAP1) is a polymorphic enzyme that shapes the peptide repertoire presented by MHC class I molecules and can regulate adaptive immune responses in cancer and autoimmunity. Common missense polymorphisms in ERAP1 modulate ... ...
