Structure-guided discovery and validation of a potent RamR inhibitor targeting efflux-mediated multidrug resistance in Salmonella typhimurium
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The emergence of multidrug-resistant (MDR) strains of Salmonella typhimurium (S. typhimurium) causes a significant global health challenge and underscores the need to develop potential antimicrobial agents. Here, we considered RamR, the major transcriptional r... ...