Generating functionally stable and antigen-specific Treg cells from effector T cells for cell therapy of inflammatory diseases
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One strategy for antigen-specific immunosuppression is to convert antigen-specific conventional T (Tconv) cells into Foxp3+ regulatory T (Treg) cells that are as stably suppressive as naturally occurring Treg (nTreg) cells. To achieve the conversion in vitro f... ...
