Intraoperative use of intrathecal methadone: Evaluation of perioperative analgesia, effectiveness and safety: A systematic review and analysis of the feasibility of its use
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Introduction: Intravenous methadone has shown an opioid-sparing effect in high-risk surgeries. It was hypothesized that intrathecal methadone might provide better effects than intravenous administration due to a direct action on ... ...