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PIVKA-II as a prognostic marker in hepatocellular carcinoma patients with normal serum alpha-fetoprotein levels

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Background: Alpha-fetoprotein (AFP) has been the primary biomarker for hepatocellular carcinoma (HCC), but a subset of patients with HCC have normal serum levels of AFP (100 mAU/mL vs. ≤100 mAU/mL). Prognostic factors for overal... ...